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Glucocorticoid receptors on mononuclear leukocytes in Alzheimer's disease

Rupprecht, R. and Frölich, L. and Mergenthaler, T. and Kornhuber, J. and Wodarz, Norbert and Riederer, P. and Maurer, K. (1990) Glucocorticoid receptors on mononuclear leukocytes in Alzheimer's disease. Psychiatry research 34 (3), pp. 237-241.

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Abstract

Several lines of evidence suggest disturbances of the hypothalamic-pituitary-adrenal (HPA) system in Alzheimer's disease (AD). In an exploration of the potential role of the glucocorticoid receptor (GR) in AD, GR density and affinity were assessed on mononuclear leukocytes of 12 AD patients and 12 healthy controls. GR binding characteristics did not differ between patients and controls or between ...

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Item Type:Article
Date:1990
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
1963690PubMed ID
Classification:
NotationType
Adrenocorticotropic Hormone/bloodMESH
AgedMESH
Alzheimer Disease/bloodMESH
FemaleMESH
HumansMESH
Hydrocortisone/bloodMESH
Hypothalamo-Hypophyseal System/physiopathologyMESH
Immunoradiometric AssayMESH
Leukocytes, Mononuclear/metabolismMESH
MaleMESH
Middle AgedMESH
Pituitary-Adrenal System/physiopathologyMESH
Receptors, Glucocorticoid/metabolismMESH
Keywords:Glucocorticoid receptors, Alzheimer’s disease, aging
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:27 Aug 2010 12:18
Last Modified:13 Mar 2014 14:01
Item ID:16333
Owner Only: item control page
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