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In vivo and in vitro effects of glucocorticoids on lymphocyte proliferation in man: relationship to glucocorticoid receptors

Rupprecht, R. and Wodarz, Norbert and Kornhuber, J. and Schmitz, B. and Wild, K. and Braner, H.-U. and Müller, O. A. and Riederer, P. (1991) In vivo and in vitro effects of glucocorticoids on lymphocyte proliferation in man: relationship to glucocorticoid receptors. Neuropsychobiology 24 (2), pp. 61-66.

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Abstract

Interrelations between the hypothalamic-pituitary-adrenal system (HPA) and the immune system represent a well-documented biological phenomenon. While in vitro administration of glucocorticoids may inhibit concanavalin A (Con A)- and phytohemagglutinin (PHA)-induced T-cell proliferation, pokeweed mitogen (PWM)-driven B-cell mitogenesis is relatively resistant to glucocorticoids. To further explore ...

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Item Type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
1966869PubMed ID
Classification:
NotationType
Adrenocorticotropic Hormone/pharmacologyMESH
AdultMESH
B-Lymphocytes/drug effectsMESH
Dexamethasone/pharmacologyMESH
FemaleMESH
Glucocorticoids/pharmacologyMESH
HumansMESH
Lymphocyte Activation/drug effectsMESH
MaleMESH
Metyrapone/pharmacologyMESH
Middle AgedMESH
Receptors, Glucocorticoid/drug effectsMESH
T-Lymphocytes/drug effectsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:27 Aug 2010 12:24
Last Modified:27 Aug 2010 12:24
Item ID:16335
Owner Only: item control page
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