Feuerstein, J. and Kalbitzer, Hans Robert and John, J. and Goody, R. S. and Wittinghofer, A. (1987) Characterisation of the metal-ion-GDP complex at the active sites of transforming and nontransforming p21 proteins by observation of the ¹⁷O-Mn superhyperfine coupling and by kinetic methods. European journal of biochemistry (= the FEBS journal) 162 (1), pp. 49-55.
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Kinetic studies on the interaction of three Ha-ras-encoded p21 proteins with GDP and MgGDP have yielded values for the association (10(6)-10(7) M-1 s-1) and dissociation (10(-3)-10(-5) s-1) rate constants at 0 degrees C. Dramatic differences in the rate constants were not observed for the three proteins. Under non-physiological conditions (absence of Mg2+), the rate constant for GDP release was ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer|
|Subjects:||500 Science > 570 Life sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||03 Sep 2010 12:42|
|Last Modified:||03 Sep 2010 12:42|