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Inhibition of murine cytotoxic T cell responses by progesterone

Mannel, D. N. and Falk, Werner and Yron, I. (1990) Inhibition of murine cytotoxic T cell responses by progesterone. Immunology letters 26 (1), pp. 89-94.

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Abstract

In the present study we evaluated the effect of sex hormone on the generation of murine cytotoxic T cell responses. We show that the in vitro CTL response was strongly inhibited by progesterone but not by E1, E2 or testosterone. Our experiments attempting to understand the mechanism of the hormone action on CTL development have revealed that the ability of the cells to generate helper signals was ...

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Item Type:Article
Date:1990
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2148927PubMed ID
Classification:
NotationType
AnimalsMESH
Cell DifferentiationMESH
Cells, CulturedMESH
Concanavalin A/diagnostic useMESH
Estradiol/physiologyMESH
Estrone/physiologyMESH
FemaleMESH
Interleukin-2/metabolismMESH
Lymphocyte Activation/physiologyMESH
MiceMESH
Mice, Inbred BALB CMESH
Mice, Inbred C3HMESH
Progesterone/physiologyMESH
Receptors, Interleukin-2/biosynthesisMESH
T-Lymphocytes/immunologyMESH
T-Lymphocytes, Cytotoxic/cytologyMESH
T-Lymphocytes, Helper-Inducer/cytologyMESH
Testosterone/physiologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:08 Sep 2010 05:22
Last Modified:13 Mar 2014 14:00
Item ID:16470
Owner Only: item control page

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