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Tumor-induced tumor necrosis factor production in macrophages

Männel, D. N. and Jänicke, R. and Westenfelder, U. and Echtenacher, B. and Kist, A. and Falk, Werner (1990) Tumor-induced tumor necrosis factor production in macrophages. Lymphokine research 9 (4), pp. 485-489.

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Abstract

Tumor-associated tumor necrosis factor (TNF) production in patients as well as a TNF-inducing membrane constituent of tumor cells have been reported. In a murine fibrosarcoma model we analyzed TNF production during growth of a tumor transplant. In situ hybridization showed that a gradually increasing number of cells within the tumor tissue became positive for TNFmRNA. Also, in spleen cells of ...

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Item Type:Article
Date:1990
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2090875PubMed ID
Classification:
NotationType
AnimalsMESH
Biological AssayMESH
Blotting, NorthernMESH
Enzyme-Linked Immunosorbent AssayMESH
Fibrosarcoma/metabolismMESH
Immunoenzyme TechniquesMESH
Interleukin-6/analysisMESH
Macrophages/metabolismMESH
MiceMESH
Mice, Inbred C3HMESH
Nucleic Acid HybridizationMESH
RNA, Messenger/geneticsMESH
Tumor Necrosis Factor-alpha/biosynthesisMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:08 Sep 2010 05:21
Last Modified:13 Mar 2014 14:00
Item ID:16471
Owner Only: item control page

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