Startseite UB

Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen

Oehm, A. and Behrmann, I. and Falk, Werner and Pawlita, M. and Maier, G. and Klas, C. and Li-Weber, M. and Richards, S. and Dhein, J. and Trauth, B. C. (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. The Journal of biological chemistry 267 (15), pp. 10709-10715.

[img]
Preview
PDF
Download (4MB)

at PubMed


Abstract

The APO-1 antigen as defined by the mouse monoclonal antibody anti-APO-1 was previously found to be expressed on the cell surface of activated human T and B lymphocytes and a variety of malignant human lymphoid cell lines. Cross-linking of the APO-1 antigen by anti-APO-1 induced programmed cell death, apoptosis, of APO-1 positive cells. To characterize the APO-1 cell surface molecule and to ...

plus


Export bibliographical data

Item Type:Article
Date:1992
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
1375228PubMed ID
Classification:
NotationType
Amino Acid SequenceMESH
Antigens, CD95MESH
Antigens, Neoplasm/isolation & purificationMESH
Antigens, Surface/geneticsMESH
Base SequenceMESH
Blotting, WesternMESH
Cell DeathMESH
Cloning, MolecularMESH
Cross-Linking ReagentsMESH
DNA/geneticsMESH
Electrophoresis, Polyacrylamide GelMESH
Enzyme-Linked Immunosorbent AssayMESH
HumansMESH
Membrane Proteins/isolation & purificationMESH
Molecular Sequence DataMESH
Multigene FamilyMESH
Nerve Growth Factors/metabolismMESH
Receptors, Cell Surface/geneticsMESH
Receptors, Nerve Growth FactorMESH
Receptors, Tumor Necrosis FactorMESH
Sequence Homology, Nucleic AcidMESH
Tumor Necrosis Factor-alpha/metabolismMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:08 Sep 2010 05:17
Last Modified:13 Mar 2014 14:01
Item ID:16492
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact