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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-164987
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.16498
Zusammenfassung
Interleukin-1 (IL-1) costimulation is required for efficient IL-2 synthesis and IL-2 receptor (IL-2R) expression of T cells. The molecular events leading to these effects are largely unknown. We utilized an IL-1-responsive and an IL-1-non-responsive subclone of the mouse thymoma cell line EL4 to investigate how IL-1 activates IL-2 gene expression. We correlated IL-2 promoter activity with the ...
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