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Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry

URN to cite this document: urn:nbn:de:bvb:355-epub-165508

Wiesner, Philipp (2010) Lipid profiling of FPLC-separated lipoprotein fractions by electrospray ionization tandem mass spectrometry. PhD, Universität Regensburg

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Abstract (English)

Glycerophospholipid and sphingolipid species and their bioactive metabolites are important regulators of lipoprotein and cell function. Aim of the study was to develop a method for lipid species profiling of separated lipoprotein classes. Methods: Human serum lipoproteins VLDL, LDL and HDL of 21 healthy fasting blood donors were separated by fast performance liquid chromatography (FPLC) from ...


Translation of the abstract (German)

Cholesterin, Glycerophospho- und Sphingolipide und deren aktive Metaboliten sind wichtige Komponenten und Regulatoren des Lipoprotein- und Zellstoffwechsels. Phosphatidylcholin und Sphingomyelin dienen als Vorläufer der Verbindungen Lysophospatidylcholine bzw. Ceramide und regulieren darüber hinaus zentrale Schritte des Lipoproteinstoffwechsels. Neben der direkten Wirkung dieser Lipide auf den ...


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Item Type:Thesis of the University of Regensburg (PhD)
Date:11 October 2010
Referee:Prof. Dr. Gerd Schmitz and PD Dr. Christa Büchler
Date of exam:14 September 2010
Institutions:Medicine > Lehrstuhl für Klinische Chemie und Laboratoriumsmedizin
Interdisciplinary Subject Network:Not selected
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:11 Oct 2010 09:42
Last Modified:13 Mar 2014 14:01
Item ID:16550
Owner Only: item control page


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