Antz, C. and Bauer, T. and Kalbacher, H. and Frank, R. and Covarrubias, M. and Kalbitzer, Hans Robert and Ruppersberg, J. P. and Baukrowitz, T. and Fakler, B. (1999) Control of K⁺ channel gating by protein phosphorylation: structural switches of the inactivation gate. Nature structural biology 6 (2), pp. 146-150.
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Fast N-type inactivation of voltage-dependent potassium (Kv) channels controls membrane excitability and signal propagation in central neurons and occurs by a 'ball-and-chain'-type mechanism. In this mechanism an N-terminal protein domain (inactivation gate) occludes the pore from the cytoplasmic side. In Kv3.4 channels, inactivation is not fixed but is dynamically regulated by protein ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer|
|Subjects:||500 Science > 570 Life sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||13 Sep 2010 08:03|
|Last Modified:||13 Sep 2010 08:03|