Praefcke, G. J. and Geyer, M. and Schwemmle, M. and Kalbitzer, Hans Robert and Herrmann, C. (1999) Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif. Journal of molecular biology 292 (2), pp. 321-332.
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hGBP1 is a GTPase with antiviral activity encoded by an interferon- activated human gene. Specific binding of hGBP1 to guanine nucleotides has been established although only two classical GTP-binding motifs were found in its primary sequence. The unique position of hGBP1 amongst known GTPases is further demonstrated by the hydrolysis of GTP to GDP and GMP. Although subsequent cleavage of ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer|
|Dewey Decimal Classification:||500 Science > 570 Life sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited on:||13 Sep 2010 07:59|
|Last modified:||13 Sep 2010 07:59|