Spoerner, Michael and Wittinghofer, Alfred and Kalbitzer, Hans Robert (2004) Perturbation of the conformational equilibria in Ras by selective mutations as studied by ³¹P NMR spectroscopy. FEBS letters 578 (3), pp. 305-310.
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Ras regulates a variety of different signal transduction pathways acting as molecular switch. It was shown by liquid and solid-state (31)P NMR spectroscopy that Ras exists in the guanosine-5'-(beta,gamma-imido)triphosphate bound form in at least two conformational states interconverting in millisecond time scale. The relative population between the two conformational states affects drastically ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Dr. Hans Robert Kalbitzer|
|Subjects:||500 Science > 570 Life sciences|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 Sep 2010 06:30|
|Last Modified:||17 Sep 2010 06:30|