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Simulations on the selectivity of 5-aminolaevulinic acid-induced fluorescence in vivo

Ackermann, G. and Abels, C. and Bäumler, W. and Langer, S. and Landthaler, M. and Lang, Elmar W. and Szeimies, R M (1998) Simulations on the selectivity of 5-aminolaevulinic acid-induced fluorescence in vivo. Journal of photochemistry and photobiology. B, Biology 47 (2-3), pp. 121-128.

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Abstract

The knowledge of the exact time course of a photosensitizer in tumour and surrounding host tissue is fundamental for effective photodynamic therapy (PDT) and fluorescence-based diagnosis. In this study the time course of porphyrin fluorescence following topical application of 5-aminolaevulinic acid (ALA) using different formulations, concentrations and incubation times has been measured in ...

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Item Type:Article
Date:1998
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Elmar Lang
Identification Number:
ValueType
10093911PubMed ID
Related URLs:
URLURL Type
http://www.sciencedirect.com/science/journal/10111344 Publisher
Classification:
NotationType
Aminolevulinic AcidMESH
AnimalsMESH
CricetinaeMESH
FluorescenceMESH
HumansMESH
MaleMESH
MesocricetusMESH
Microscopy, Fluorescence/methodsMESH
Middle AgedMESH
Models, BiologicalMESH
Photosensitizing AgentsMESH
Keywords:Aminolaevulinic acid (ALA); Protoporphyrin IX; Topical; Compartment model- Pharmacokinetics
Subjects:500 Science > 570 Life sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Gertraud Kellers
Deposited On:22 Sep 2010 08:21
Last Modified:22 Sep 2010 08:21
Item ID:16691
Owner Only: item control page
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