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Histamine H4 receptor agonists

Igel, Patrick and Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.

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Abstract

Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a potential drug target, for instance, for the treatment of inflammatory and allergic diseases. Potent and selective ligands including agonists are required as pharmacological tools to study the role of the H4R in vitro and in vivo. Many H4R agonists, which were identified among already known histamine ...

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Item Type:Article
Date:15 December 2010
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.1016/j.bmcl.2010.10.041DOI
21044842PubMed ID
Related URLs:
URLURL Type
http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6TF9-517J25J-7-W&_cdi=5221&_user=616165&_pii=S0960894X10014927&_origin=search&_coverDate=10%2F14%2F2010&_sk=999999999&view=c&wchp=dGLbVlb-zSkWA&md5=681c7952de46fdc1e70685f5efd43b26&ie=/sdarticle.pdfPublisher
Keywords:H4 receptor selectivity; acylguanidines; arylbenzimidazoles; clozapine analogues; cyanoguanidines; indoles; oximes
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:18 Oct 2010 14:39
Last Modified:17 Nov 2010 17:27
Item ID:17078
Owner Only: item control page
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