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Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs

Merfort, Irmgard und Heilmann, Jörg und Weiss, Manfred und Pietta, Piergiorgio und Gardana, Claudio (1996) Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs. Planta medica 62 (4), S. 289-292.

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Zusammenfassung

3,4-Dihydroxyphenylacetic acid (I), 3-hydroxyphenylacetic acid (II), and 3-(4-hydroxyphenyl)propionic acid (III), metabolites which arise from quercetin glycosides, resp., from flavones and probably from procyanidins by the human intestinal microflora, have been tested for their effects on oxygen radical prodn. by human PNMs stimulated with FMLP or opsonized zymosan. Oxygen radicals were detected ...

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Dokumentenart:Artikel
Datum:1996
Zusätzliche Informationen (Öffentlich):CAN 125:292771 1-10 Pharmacology 102-32-9 (3,4-Dihydroxyphenylacetic acid); 501-97-3 (3-(4-Hydroxyphenyl)propionic acid); 621-37-4 (3-Hydroxyphenylacetic acid) Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), MFM (Metabolic formation), BIOL (Biological study), FORM (Formation, nonpreparative) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs); 117-39-5 (Quercetine) Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs); 7722-84-1 (Hydrogen peroxide); 9003-99-0 (Peroxidase) Role: RCT (Reactant), RACT (Reactant or reagent) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
1996:618490Andere
Stichwörter / Keywords:Luminescence Neutrophil (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) Radicals Role: ANT (Analyte), BPR (Biological process), BSU (Biological study, unclassified), ANST (Analytical study), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence Procyanidins Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) Flavonoids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (oxo, radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) radical scavenger flavonoid metabolite
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:15 Okt 2010 10:15
Zuletzt geändert:15 Okt 2010 10:15
Dokumenten-ID:17174
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