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Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs

Merfort, Irmgard and Heilmann, Jörg and Weiss, Manfred and Pietta, Piergiorgio and Gardana, Claudio (1996) Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs. Planta medica 62 (4), pp. 289-292.

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Abstract

3,4-Dihydroxyphenylacetic acid (I), 3-hydroxyphenylacetic acid (II), and 3-(4-hydroxyphenyl)propionic acid (III), metabolites which arise from quercetin glycosides, resp., from flavones and probably from procyanidins by the human intestinal microflora, have been tested for their effects on oxygen radical prodn. by human PNMs stimulated with FMLP or opsonized zymosan. Oxygen radicals were detected ...

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Item Type:Article
Date:1996
Additional information (public):CAN 125:292771 1-10 Pharmacology 102-32-9 (3,4-Dihydroxyphenylacetic acid); 501-97-3 (3-(4-Hydroxyphenyl)propionic acid); 621-37-4 (3-Hydroxyphenylacetic acid) Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), MFM (Metabolic formation), BIOL (Biological study), FORM (Formation, nonpreparative) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs); 117-39-5 (Quercetine) Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs); 7722-84-1 (Hydrogen peroxide); 9003-99-0 (Peroxidase) Role: RCT (Reactant), RACT (Reactant or reagent) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
1996:618490Other
Keywords:Luminescence Neutrophil (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) Radicals Role: ANT (Analyte), BPR (Biological process), BSU (Biological study, unclassified), ANST (Analytical study), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence Procyanidins Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) Flavonoids Role: BPR (Biological process), BSU (Biological study, unclassified), BIOL (Biological study), PROC (Process) (oxo, radical scavenger activity of flavonoid metabolites detd. by inhibition of chemiluminescence in human PMNs) radical scavenger flavonoid metabolite
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Joerg Heilmann
Deposited On:15 Oct 2010 10:15
Last Modified:15 Oct 2010 10:15
Item ID:17174
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