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Cytotoxic cardenolides and antibacterial terpenoids from Crossopetalum gaumeri

Ankli, A. and Heilmann, Jörg and Heinrich, M. and Sticher, O. (2000) Cytotoxic cardenolides and antibacterial terpenoids from Crossopetalum gaumeri. Phytochemistry 54 (5), pp. 531-537.

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Abstract

From the methanol ext. of the roots of Crossopetalum gaumeri, four new highly cytotoxic cardenolides, securigenin-3beta -O-beta -6-deoxyguloside, 19-hydroxy-sarmentogenin-3beta -O-beta -6-deoxyguloside, sarmentogenin-3beta -O-[alpha -allosyl-(1-> 4)-beta -6-deoxyalloside], and securigenin-3beta -O-[alpha -allosyl-(1->4)-beta -6-deoxyalloside] were isolated. The dichloromethane ext. afforded the ...

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Item Type:Article
Date:2000
Additional information (public):CAN 133:249671 11-1 Plant Biochemistry 1258-84-0 (Pristimerin); 34157-83-0 (Celastrol); 39903-21-4 Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), BIOL (Biological study), OCCU (Occurrence) (antibacterial terpenoids from Crossopetalum gaumeri); 295323-25-0P; 295323-26-1P; 342775-67-1P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (antibacterial terpenoids from Crossopetalum gaumeri); 17291-05-3 (Ourateacatechin) Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (cytotoxic agents from Crossopetalum gaumeri); 22333-73-9 Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), BIOL (Biological study), OCCU (Occurrence) (cytotoxic cardenolides from Crossopetalum gaumeri); 295323-22-7P; 295323-23-8P; 295323-24-9P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (cytotoxic cardenolides from Crossopetalum gaumeri)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
2000:531441Other
Keywords:Antibacterial agents (antibacterial terpenoids from Crossopetalum gaumeri) Diterpenes Triterpenes Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) Steroids Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ca cytotoxic cardenolides from Crossopetalum gaumeri) New natural products (cardenolides and terpenoids from Crossopetalum gaumeri) Crossopetalum gaumeri (cytotoxic cardenolides and antibacterial terpenoids from Crossopetalum gaumeri) Cytotoxic agents (cytotoxic cardenolides from Crossopetalum gaumeri) Molecular structure (of cardenolides and terpenoids from Crossopetalum gaumeri) cardenolide Crossopetalum cytotoxic agent terpenoid Crossopetalum antibacterial agent
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Joerg Heilmann
Deposited On:15 Oct 2010 10:27
Last Modified:15 Oct 2010 10:27
Item ID:17182
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