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Antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum

Gertsch, Juerg und Tobler, Rebekka Thoeni und Brun, Reto und Sticher, Otto und Heilmann, Jörg (2003) Antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum. Planta medica 69 (5), S. 420-424.

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Zusammenfassung

Using activity against Candida albicans as a lead, the bioactivity-guided fractionation of the CH2Cl2 ext. of P. piscatorum led to the isolation of the arylnaphthalide lignan justicidin B (I), which was found to be present in high amts., and a new C-11 hydroxylated deriv. that we named piscatorin (II). We provide evidence that I is the main active principle of P. piscatorum, showing the same ...

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Dokumentenart:Artikel
Datum:2003
Zusätzliche Informationen (Öffentlich):CAN 139:377900 11-1 Plant Biochemistry 623943-73-7P (Piscatorin) Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum); 17951-19-8P (Justicidin B) Role: BSU (Biological study, unclassified), PUR (Purification or recovery), BIOL (Biological study), PREP (Preparation) (antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2003:512784Andere
Stichwörter / Keywords:Antibiotics Fungicides Phyllanthus piscatorum Protozoacides (antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum) Toxins Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (cytotoxins antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum) Molecular structure (of piscatorin (arylnaphthalide lignan) New natural products (piscatorin (arylnaphthalide lignan) Pesticides (piscicides antifungal, antiprotozoal, cytotoxic and piscicidal properties of justicidin B and a new arylnaphthalide lignan from Phyllanthus piscatorum) Phyllanthus justicidin B piscatorin fungicide protozoacide cytotoxin piscicide
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:18 Okt 2010 12:29
Zuletzt geändert:18 Okt 2010 12:29
Dokumenten-ID:17213
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