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Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx

Winkelmann, Karin and San, Metin and Kypriotakis, Zacharias and Skaltsa, Helen and Bosilij, Blazenka and Heilmann, Jörg (2003) Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx. Zeitschrift für Naturforschung: Section C, A journal of biosciences 58 (7/8), pp. 527-532.

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Abstract

Two new bicyclic acylphloroglucinol derivs., hypercalyxone A (I) and B (II), were isolated from the petroleum ether ext. of the aerial parts of H. amblycalyx, together with 2 further compds. (1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylpropan-1-one [III] and 1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylbutan-1-one [IV]), which have been ...

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Item Type:Article
Date:2003
Additional information (public):CAN 140:178249 11-1 Plant Biochemistry 1617-70-5 (Lup-20(29)-en-3-one) Role: BSU (Biological study, unclassified), BIOL (Biological study) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx); 658702-60-4P (Hypercalyxone A); 658702-61-5P (Hypercalyxone B) Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx); 658702-62-6P ((+)-1-[5,7-Dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylpropan-1-one); 658702-63-7P ((+)-1-[5,7-Dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylbutan-1-one) Role: BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), PREP (Preparation) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
2003:716938Other
Keywords:Antibiotics Antitumor agents Hypericum amblycalyx (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx) Toxins Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (cytotoxins antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx) New natural products (hypercalyxone A (bicyclic acylphloroglucinol deriv.) New natural products (hypercalyxone B (bicyclic acylphloroglucinol deriv.) Molecular structure (of hypercalyxones (bicyclic acylphloroglucinol derivs.) antibacterial cytotoxin prenylated bicyclic acylphloroglucinol deriv Hypericum
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Owner: Prof. Dr. Joerg Heilmann
Deposited On:18 Oct 2010 12:37
Last Modified:18 Oct 2010 12:37
Item ID:17219
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