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Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx

Winkelmann, Karin und San, Metin und Kypriotakis, Zacharias und Skaltsa, Helen und Bosilij, Blazenka und Heilmann, Jörg (2003) Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx. Zeitschrift für Naturforschung: Section C, A journal of biosciences 58 (7/8), S. 527-532.

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Zusammenfassung

Two new bicyclic acylphloroglucinol derivs., hypercalyxone A (I) and B (II), were isolated from the petroleum ether ext. of the aerial parts of H. amblycalyx, together with 2 further compds. (1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylpropan-1-one [III] and 1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylbutan-1-one [IV]), which have been ...

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Dokumentenart:Artikel
Datum:2003
Zusätzliche Informationen (Öffentlich):CAN 140:178249 11-1 Plant Biochemistry 1617-70-5 (Lup-20(29)-en-3-one) Role: BSU (Biological study, unclassified), BIOL (Biological study) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx); 658702-60-4P (Hypercalyxone A); 658702-61-5P (Hypercalyxone B) Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx); 658702-62-6P ((+)-1-[5,7-Dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylpropan-1-one); 658702-63-7P ((+)-1-[5,7-Dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylbutan-1-one) Role: BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), PREP (Preparation) (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2003:716938Andere
Stichwörter / Keywords:Antibiotics Antitumor agents Hypericum amblycalyx (antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx) Toxins Role: BSU (Biological study, unclassified), NPO (Natural product occurrence), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (cytotoxins antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivs. from Hypericum amblycalyx) New natural products (hypercalyxone A (bicyclic acylphloroglucinol deriv.) New natural products (hypercalyxone B (bicyclic acylphloroglucinol deriv.) Molecular structure (of hypercalyxones (bicyclic acylphloroglucinol derivs.) antibacterial cytotoxin prenylated bicyclic acylphloroglucinol deriv Hypericum
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:18 Okt 2010 12:37
Zuletzt geändert:18 Okt 2010 12:37
Dokumenten-ID:17219
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