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Cytotoxicity and immunomodulating characteristics of labdane diterpenes from Marrubium cylleneum and Marrubium velutinum

Karioti, Anastasia und Skopeliti, Margarita und Tsitsilonis, Ourania und Heilmann, Jörg und Skaltsa, Helen (2007) Cytotoxicity and immunomodulating characteristics of labdane diterpenes from Marrubium cylleneum and Marrubium velutinum. Phytochemistry 68 (11), S. 1587-1594.

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Zusammenfassung

From the aerial parts of Marrubium cylleneum, 1 labdane nor-diterpene was isolated together with 2 labdane diterpenes, hitherto not known as natural products. The structures of the isolated compds. were established by means of NMR [1H-1H-COSY, 1H-13C-HSQC, HMQC-TOCSY, HMBC, NOESY] and MS spectral analyses. Several diterpenoids from M. cylleneum and M. velutinum were tested for their cytotoxic ...

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Dokumentenart:Artikel
Datum:2007
Zusätzliche Informationen (Öffentlich):CAN 147:203316 1-6 Pharmacology 465-92-9P; 19898-90-9P; 19906-99-1P; 72010-01-6P; 72029-64-2P; 170554-74-2P; 175861-92-4P; 176019-14-0P; 857901-78-1P; 857901-80-5P; 858341-33-0P; 944795-71-5P; 944795-73-7P Role: PAC (Pharmacological activity), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (labdane diterpenes from Marrubium cylleneum and Marrubium velutinum, purifn., mol. structure, cytotoxicity, and immunomodulation)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2007:588022Andere
Stichwörter / Keywords:Antitumor agents Cytotoxicity Human Immunosuppressants Lymphocyte Marrubium cylleneum Marrubium velutinum Molecular structure Natural products (labdane diterpenes from Marrubium cylleneum and Marrubium velutinum, purifn., mol. structure, cytotoxicity, and immunomodulation) Diterpenes Role: PAC (Pharmacological activity), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (labdane labdane diterpenes from Marrubium cylleneum and Marrubium velutinum, purifn., mol. structure, cytotoxicity, and immunomodulation) Diterpenes Role: PAC (Pharmacological activity), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (norditerpenes labdane diterpenes from Marrubium cylleneum and Marrubium velutinum, purifn., mol. structure, cytotoxicity, and immunomodulation) labdane diterpene Marrubium mol structure cytotoxicity immunomodulator antitumor
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Ja
Eingebracht am:18 Okt 2010 13:18
Zuletzt geändert:18 Okt 2010 13:18
Dokumenten-ID:17231
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