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Xanthohumol feeding does not impair organ function and homeostasis in mice

Dorn, Christoph and Bataille, Frauke and Gaebele, Erwin and Heilmann, Jörg and Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homeostasis in mice. Food and chemical toxicology 48 (7), pp. 1890-1897.

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Abstract

Xanthohumol, the major prenylated chalcone found in hops, is known to exert several beneficial effects but only few studies evaluated the safety profile of this natural compd. with in part discrepant results. Here, the authors fed female BALB/c mice with a std. diet supplemented with xanthohumol for 3 wk, and thus, achieved a daily dose of .apprx.1000 mg xanthohumol/kg body wt. There were no ...

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Item Type:Article
Date:2010
Additional information (public):CAN 153:165382 4-3 Toxicology 6754-58-1 (Xanthohumol) Role: ADV (Adverse effect, including toxicity), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice); 50-99-7 (D-Glucose); 57-13-6 (Urea); 60-27-5 (Creatinine); 7440-09-7 (Potassium); 7440-23-5 (Sodium); 9000-86-6 (ALT); 9000-97-9 (AST); 9001-62-1 (Lipase); 9005-79-2 (Glycogen); 330196-64-0 (Cytochrome P 450 1A2); 330196-93-5 (Cytochrome P 450 2E1); 343627-37-2 (Cytochrome P 450 3A11) Role: BSU (Biological study, unclassified), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice)
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
2010:710182Other
Keywords:CD antigens Role: BSU (Biological study, unclassified), BIOL (Biological study) (CD54 xanthohumol feeding does not impair organ function and homeostasis in mice) Cell adhesion molecules Role: BSU (Biological study, unclassified), BIOL (Biological study) (ICAM-1 (intercellular adhesion mol. 1) xanthohumol feeding does not impair organ function and homeostasis in mice) Proteins Role: BSU (Biological study, unclassified), BIOL (Biological study) (blood xanthohumol feeding does not impair organ function and homeostasis in mice) Toxins Role: BSU (Biological study, unclassified), BIOL (Biological study) (endotoxins xanthohumol feeding does not impair organ function and homeostasis in mice) Liver disease (fibrosis xanthohumol feeding does not impair organ function and homeostasis in mice) Fibrosis Injury (hepatic xanthohumol feeding does not impair organ function and homeostasis in mice) Liver disease (injury xanthohumol feeding does not impair organ function and homeostasis in mice) Collagens Role: BSU (Biological study, unclassified), BIOL (Biological study) (type I xanthohumol feeding does not impair organ function and homeostasis in mice) Animal organ Biomarkers Blood serum Colon Growth Heart Hepatitis Hepatotoxicity Homeostasis Human Humulus lupulus Kidney Liver Lung Pancreas Spleen Thymus gland (xanthohumol feeding does not impair organ function and homeostasis in mice) Albumins Cytokines Enzymes Gene Interleukin 1alpha Monocyte chemoattractant protein-1 Transforming growth factor beta Tumor necrosis factors Role: BSU (Biological study, unclassified), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice) xanthohumol feeding organ function homeostasis toxicity xanthohumol feeding
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Dr. Joerg Heilmann
Deposited On:18 Oct 2010 13:59
Last Modified:18 Oct 2010 13:59
Item ID:17249
Owner Only: item control page
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