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Xanthohumol feeding does not impair organ function and homeostasis in mice

Dorn, Christoph und Bataille, Frauke und Gaebele, Erwin und Heilmann, Jörg und Hellerbrand, Claus (2010) Xanthohumol feeding does not impair organ function and homeostasis in mice. Food and chemical toxicology 48 (7), S. 1890-1897.

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Zusammenfassung

Xanthohumol, the major prenylated chalcone found in hops, is known to exert several beneficial effects but only few studies evaluated the safety profile of this natural compd. with in part discrepant results. Here, the authors fed female BALB/c mice with a std. diet supplemented with xanthohumol for 3 wk, and thus, achieved a daily dose of .apprx.1000 mg xanthohumol/kg body wt. There were no ...

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Dokumentenart:Artikel
Datum:2010
Zusätzliche Informationen (Öffentlich):CAN 153:165382 4-3 Toxicology 6754-58-1 (Xanthohumol) Role: ADV (Adverse effect, including toxicity), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice); 50-99-7 (D-Glucose); 57-13-6 (Urea); 60-27-5 (Creatinine); 7440-09-7 (Potassium); 7440-23-5 (Sodium); 9000-86-6 (ALT); 9000-97-9 (AST); 9001-62-1 (Lipase); 9005-79-2 (Glycogen); 330196-64-0 (Cytochrome P 450 1A2); 330196-93-5 (Cytochrome P 450 2E1); 343627-37-2 (Cytochrome P 450 3A11) Role: BSU (Biological study, unclassified), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice)
Institutionen:Medizin > Lehrstuhl für Innere Medizin I
Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2010:710182Andere
Stichwörter / Keywords:CD antigens Role: BSU (Biological study, unclassified), BIOL (Biological study) (CD54 xanthohumol feeding does not impair organ function and homeostasis in mice) Cell adhesion molecules Role: BSU (Biological study, unclassified), BIOL (Biological study) (ICAM-1 (intercellular adhesion mol. 1) xanthohumol feeding does not impair organ function and homeostasis in mice) Proteins Role: BSU (Biological study, unclassified), BIOL (Biological study) (blood xanthohumol feeding does not impair organ function and homeostasis in mice) Toxins Role: BSU (Biological study, unclassified), BIOL (Biological study) (endotoxins xanthohumol feeding does not impair organ function and homeostasis in mice) Liver disease (fibrosis xanthohumol feeding does not impair organ function and homeostasis in mice) Fibrosis Injury (hepatic xanthohumol feeding does not impair organ function and homeostasis in mice) Liver disease (injury xanthohumol feeding does not impair organ function and homeostasis in mice) Collagens Role: BSU (Biological study, unclassified), BIOL (Biological study) (type I xanthohumol feeding does not impair organ function and homeostasis in mice) Animal organ Biomarkers Blood serum Colon Growth Heart Hepatitis Hepatotoxicity Homeostasis Human Humulus lupulus Kidney Liver Lung Pancreas Spleen Thymus gland (xanthohumol feeding does not impair organ function and homeostasis in mice) Albumins Cytokines Enzymes Gene Interleukin 1alpha Monocyte chemoattractant protein-1 Transforming growth factor beta Tumor necrosis factors Role: BSU (Biological study, unclassified), BIOL (Biological study) (xanthohumol feeding does not impair organ function and homeostasis in mice) xanthohumol feeding organ function homeostasis toxicity xanthohumol feeding
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Ja
Eingebracht am:18 Okt 2010 13:59
Zuletzt geändert:18 Okt 2010 13:59
Dokumenten-ID:17249
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