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Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics

Brusch, Lutz and Cuniberti, Gianaurelio and Bertau, Martin (2004) Model evaluation for glycolytic oscillations in yeast biotransformations of xenobiotics. Biophysical Chemistry 109 (3), pp. 413-426.

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Other URL: http://dx.doi.org/10.1016/j.bpc.2003.12.004


Abstract

Anaerobic glycolysis in yeast perturbed by the reduction of xenobiotic ketones is studied numerically in two models which possess the same topology but different levels of complexity. By comparing both models' predictions for concentrations and fluxes as well as steady or oscillatory temporal behavior we answer the question what phenomena require what kind of minimum model abstraction. While mean ...

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Item Type:Article
Date:June 2004
Institutions:Physics > Institute of Theroretical Physics > Retired Professors > Group Gianaurelio Cuniberti
Projects:Graduiertenkolleg Nichtlinearität und Nichtgleichgewicht, Volkswagen Stiftung: Molecular Computing
Identification Number:
ValueType
q-bio/0404036arXiv ID
10.1016/j.bpc.2003.12.004DOI
Keywords:Glycolysis; Metabolic oscillations; Model; Biotransformation
Subjects:500 Science > 530 Physics
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Redakteur Physik
Deposited On:20 Mar 2007
Last Modified:13 Mar 2014 10:02
Item ID:1734
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