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Development of new anti-estrogens and their effects on DMBA-induced hormone dependent mammary tumors of the rat

Schönenberger, Helmut and Kranzfelder, G. and Schneider, M. (1981) Development of new anti-estrogens and their effects on DMBA-induced hormone dependent mammary tumors of the rat. In: Bastert, Gunther, (ed.) Thymusaplastic nude mice and rats in clinical oncology: proceedings of the symposium at the Klinikum der Johann-Wolfgang-Goethe-Universität. Frankfurt am Main, June 11-15, 1979. Fischer, Stuttgart, pp. 205-211. ISBN 3-437-10683-X; 0-89574-154-7.

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Abstract

3,4-di(3'-hydroxyphenyl)-hexane (I) [68266-24-0], 3,3'-dihydroxy-alpha ,beta -diethylstilbene (II) [80149-87-7], 3,4-epoxy-3,4-di(4'-hydroxyphenyl)-hexane (III) [6052-82-0], and 3,4-epoxy-3,4-di(3'-hydroxyphenyl)-hexane (IV) [80149-95-7] all inhibited DMBA [57-97-6]-induced, hormone-dependent, mammary carcinoma in rats. I was also prophylactic against DMBA induction of mammary carcinoma. ...

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Item Type:Book Section
Date:1981
Additional Information (public):CAN 96:97886 2-4 Mammalian Hormones 50-28-2 Role: BIOL (Biological study) (mammary cancer cell response to antiestrogens inhibition by); 57-97-6 Role: BIOL (Biological study) (mammary carcinoma from, antiestrogens inhibition of); 6052-82-0; 68266-24-0; 80149-87-7; 80149-95-7 Role: BIOL (Biological study) (mammary carcinoma inhibition by)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
ValueType
1982:97886Other
Keywords:Neoplasm inhibitors (antiestrogens) Estrogens Role: BSU (Biological study, unclassified), BIOL (Biological study) (inhibitors, mammary carcinoma inhibition by) Carcinoma (of mammary gland, from DMBA, antiestrogens inhibition of) Animal cell (MCF-7, growth of, antiestrogens inhibition of, estradiol antagonism of) Mammary gland (neoplasm, carcinoma, from DMBA, antiestrogens inhibition of) antiestrogen mammary carcinoma DMBA breast cancer antiestrogen estrogen antagonist mammary tumor
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Deposited On:15 Nov 2010 14:21
Last Modified:15 Nov 2010 14:21
Item ID:17630
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