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Development of new anti-estrogens and their effects on DMBA-induced hormone dependent mammary tumors of the rat

Schönenberger, Helmut and Kranzfelder, G. and Schneider, M. (1981) Development of new anti-estrogens and their effects on DMBA-induced hormone dependent mammary tumors of the rat. In: Bastert, Gunther, (ed.) Thymusaplastic nude mice and rats in clinical oncology: proceedings of the symposium at the Klinikum der Johann-Wolfgang-Goethe-Universität. Frankfurt am Main, June 11-15, 1979. Fischer, Stuttgart, pp. 205-211. ISBN 3-437-10683-X; 0-89574-154-7.

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Abstract

3,4-di(3'-hydroxyphenyl)-hexane (I) [68266-24-0], 3,3'-dihydroxy-alpha ,beta -diethylstilbene (II) [80149-87-7], 3,4-epoxy-3,4-di(4'-hydroxyphenyl)-hexane (III) [6052-82-0], and 3,4-epoxy-3,4-di(3'-hydroxyphenyl)-hexane (IV) [80149-95-7] all inhibited DMBA [57-97-6]-induced, hormone-dependent, mammary carcinoma in rats. I was also prophylactic against DMBA induction of mammary carcinoma. ...

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Item Type:Book Section
Date:1981
Additional information (public):CAN 96:97886 2-4 Mammalian Hormones 50-28-2 Role: BIOL (Biological study) (mammary cancer cell response to antiestrogens inhibition by); 57-97-6 Role: BIOL (Biological study) (mammary carcinoma from, antiestrogens inhibition of); 6052-82-0; 68266-24-0; 80149-87-7; 80149-95-7 Role: BIOL (Biological study) (mammary carcinoma inhibition by)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
ValueType
1982:97886Other
Keywords:Neoplasm inhibitors (antiestrogens) Estrogens Role: BSU (Biological study, unclassified), BIOL (Biological study) (inhibitors, mammary carcinoma inhibition by) Carcinoma (of mammary gland, from DMBA, antiestrogens inhibition of) Animal cell (MCF-7, growth of, antiestrogens inhibition of, estradiol antagonism of) Mammary gland (neoplasm, carcinoma, from DMBA, antiestrogens inhibition of) antiestrogen mammary carcinoma DMBA breast cancer antiestrogen estrogen antagonist mammary tumor
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:15 Nov 2010 14:21
Last Modified:15 Nov 2010 14:21
Item ID:17630
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