Spruss, Thilo and Gust, Ronald and Müller, Richard and Engel, Juergen and Schönenberger, Helmut (1990) Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II). Archiv der Pharmazie 323 (2), pp. 99-102.
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Abstract
[(S,S)-1,2-Bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum (II) [(S,S)-I shows a strong and dose-dependent effect on the hormone-dependent MXT mammary carcinoma of the mouse. R,R/S,S-I is markedly less active. Other I analogs were also tested.
| Item Type: | Article | ||||
|---|---|---|---|---|---|
| Additional information (public): | CAN 112:191483 1-6 Pharmacology 7440-06-4D (Platinum); 91265-66-6; 91326-61-3; 91326-62-4; 105856-23-3; 111086-58-9; 126735-37-3 Role: BIOL (Biological study) (mammary carcinoma inhibition by, hormone dependence in) | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger | ||||
| Projects: | SFB 234 | ||||
| Identification Number: |
| ||||
| Keywords: | Neoplasm inhibitors (carcinoma, [bis(hydroxyphenyl)ethylenediamine]dichloroplatinum(II) as, in mammary gland, hormone dependence in) Mammary gland (neoplasm, carcinoma, inhibition of, by [bis(hydroxyphenyl)ethylendiamine]dichloroplatinum(II), hormone dependence in) platinum complex mammary carcinoma inhibition hydroxyphenylethylenediaminedichloroplatinum mammary carcinoma inhibition | ||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Yes | ||||
| Owner: | Petra Gürster | ||||
| Deposited On: | 12 Nov 2010 08:16 | ||||
| Last Modified: | 12 Nov 2010 08:16 | ||||
| Item ID: | 17685 |
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