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Optimization of cisplatin for the treatment of hormone dependent tumoral diseases Part.1. Use of steroidal ligands

Gust, Ronald and Beck, Wolfgang and Jaouen, Gerard and Schönenberger, Helmut (2009) Optimization of cisplatin for the treatment of hormone dependent tumoral diseases Part.1. Use of steroidal ligands. Coordination Chemistry Reviews 253 (21-22), pp. 2742-2759.

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Abstract

A review. Platinum complexes such as cisplatin and carboplatin are metal based drugs, which are widely used in cancer chemotherapy. However, in the current therapy of hormone-dependent breast and prostate cancer they are not established. This might be the result of intrinsic and acquired resistance of the tumors during the therapy. Therefore, several attempts were done to design platinum ...

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Item Type:Article
Date:2009
Additional information (public):CAN 151:519961 1-0 Pharmacology 15663-27-1 (Cisplatin) Role: PAC (Pharmacological activity), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (optimization of cisplatin for the treatment of hormone dependent tumoral diseases Part.1. Use of steroidal ligands); 41575-94-4 (Carboplatin) Role: PAC (Pharmacological activity), THU (Therapeutic use), BIOL (Biological study), USES (Uses) (optimization of cisplatin for treatment of hormone dependent tumoral diseases)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
ValueType
2009:1192422Other
Keywords:Antitumor agent resistance Antitumor agent resistance Complexation Mammary gland Prostate gland (optimization of cisplatin for treatment of hormone dependent tumoral diseases) DNA Estrogen receptors Role: BSU (Biological study, unclassified), BIOL (Biological study) (optimization of cisplatin for treatment of hormone dependent tumoral diseases) review cisplatin carboplatin breast prostate cancer antitumor resistance
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:09 Nov 2010 12:57
Last Modified:12 Nov 2010 06:36
Item ID:17723
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