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(1,2-Diphenylethylenediamine)-platinum(II) complex compounds

Schönenberger, Helmut and Wappes, Beate and Jennerwein, Margaretha and Von Angerer, Erwin and Engel, Juergen (1984) (1,2-Diphenylethylenediamine)-platinum(II) complex compounds.

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Abstract

The prepn. of antitumor pharmaceuticals contg. (1,2-diphenylethylenediamine) Pt(II)-complexes I (where R1, R2, R3, R4, same or different, are: H, OH, C1-6 alkoxy, substituted C2-6 alkanoyloxy or C3-6 alkenoxyloxy, of which at least one R group is not H; X = physiol. tolerable anion) is given. Thus, (+)-dichloro-[1,2-bis-(4-hydroxyphenyl)ethylenediamine]platinum(II) (II) [91326-62-4], dissolved in ...

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Item Type:Patent
Date:1984
Additional information (public):CAN 102:32242 63-6 Pharmaceuticals Patent 19840823 58520-04-0 Role: RCT (Reactant), RACT (Reactant or reagent) (demethylation of); 1142-15-0P Role: PREP (Preparation) (prepn. and condensation of azides); 93913-17-8P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and hydrolysis of); 3839-46-1P Role: RCT (Reactant), PREP (Preparation), RACT (Reactant or reagent) (prepn. and methylation of); 91548-23-1P; 93913-15-6P; 93913-16-7P; 93913-18-9P; 93913-19-0P; 93913-20-3P; 93913-21-4P; 93913-22-5P; 93913-23-6P; 93913-24-7P; 93913-25-8P; 93913-26-9P; 93913-27-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction of, with potassium tetrachloroplatinate); 91326-61-3P; 91326-62-4P; 91326-63-5P; 93856-27-0P; 93856-28-1P; 93856-29-2P; 93856-30-5P; 93856-31-6P; 93856-32-7P; 93856-33-8P; 93856-34-9P; 93856-35-0P; 93922-81-7P; 93983-45-0P Role: PREP (Preparation) (prepn. of, as antitumor pharmaceutical); 5445-51-2 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with dichlorobis(hydroxyphenyl)ethylenediamineplatinum); 10025-99-7 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with diphenylethylenediamine derivs.); 91548-22-0 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with potassium tetrachloroplatinate) A1 DE 83-3305636 19830218
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
ValueType
1985:32242Other
84-3405611 3405611Other
Keywords:Neoplasm inhibitors ((diphenylethylenediamine) platinum II complexes) diphenylethylenediamine platinum complex formulation antitumor diphenylethylenediamine platinum complex
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Petra Gürster
Deposited On:15 Nov 2010 15:30
Last Modified:15 Nov 2010 15:30
Item ID:18061
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