Engel, Juergen and Bork, Angelika and Nubert, Ingomar and Schönenberger, Helmut (1988) Synthesis of carbon-14-labeled anpirtoline. Archiv der Pharmazie 321 (11), pp. 821-822.
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Abstract
The title compd. (I) was prepd. from 1-methyl-4-piperidinethiol. The key step was reaction of 4-piperidinethiol with 2,6-dichloropyridine-2,6-14C2.
| Item Type: | Article | ||||
|---|---|---|---|---|---|
| Additional information (public): | CAN 110:75271 27-16 Heterocyclic Compounds (One Hetero Atom) 1072-99-7 Role: RCT (Reactant), RACT (Reactant or reagent) (acylation of, with chloroformate); 99201-89-5P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and acylation of, with chloroformate); 99228-36-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and hydrolysis of); 99201-88-4P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and neutralization of); 99201-86-2P (4-Mercaptopiperidine hydrochloride) Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction of, with labeled dichloropyridine); 118688-35-0P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 70735-32-9 Role: RCT (Reactant), RACT (Reactant or reagent) (substitution reaction of, with mercaptopiperidine) | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger | ||||
| Identification Number: |
| ||||
| Keywords: | anpirtoline carbon 14 piperidinethiol substitution chloropyridine carbon labeled | ||||
| Subjects: | 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | Yes, this version has been refereed | ||||
| Created at the University of Regensburg: | Unknown | ||||
| Owner: | Petra Gürster | ||||
| Deposited On: | 22 Nov 2010 13:35 | ||||
| Last Modified: | 22 Nov 2010 13:35 | ||||
| Item ID: | 18118 |
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