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Synthesis and testing the cardiocirculatory effects of N-(3'-methoxybenzamidomethyl)-D-norephedrine and analogous compounds

Schönenberger, Helmut and Petter, Alfred and Kuehling, Volker and Bindl, Ludwig (1976) Synthesis and testing the cardiocirculatory effects of N-(3'-methoxybenzamidomethyl)-D-norephedrine and analogous compounds. Archiv der Pharmazie 309 (4), pp. 289-301.

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Twenty-six substituted N-benzamidomethyl and 3 N-(diphenylacetamido)methyl amines were prepd. by coupling I groups (R1 = H or MeO; R2 = H, Me MeO, EtO, PrO, or Cl; R3 = H, MeO, or Cl) and Ph2CHCONHCH2 groups, resp., to the N atom of phenylethylamine, amphetamine, phenylethanolamine, norephedrine, ephedrine, norfenefrine, and noradrenaline. Tests on the isolated guinea pig heart showed that the ...


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Item Type:Article
Additional Information (public):CAN 85:40643 1-3 Pharmacodynamics 15687-41-9 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (cardiovascular activity of, norephedrine analogs in relation to); 59630-56-7P; 59630-57-8P; 59630-58-9P; 59630-59-0P; 59630-60-3P; 59630-61-4P; 59630-62-5P; 59630-63-6P; 59630-64-7P; 59630-65-8P; 59630-66-9P; 59630-67-0P; 59630-68-1P; 59630-69-2P; 59630-70-5P; 59630-71-6P; 59630-72-7P; 59630-73-8P; 59630-74-9P; 59630-75-0P; 59630-76-1P; 59630-77-2P; 59630-78-3P; 59630-79-4P; 59630-80-7P; 59630-81-8P; 59630-82-9P; 59643-15-1P; 59643-16-2P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and cardiovascular activity of); 6282-02-6P; 13855-74-8P; 40478-07-7P; 57428-72-5P; 59630-85-2P; 59630-86-3P; 59630-87-4P; 59630-88-5P; 59630-89-6P; 59630-90-9P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and chlorination of); 59630-83-0P; 59630-84-1P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Identification Number:
Keywords:Circulation Heart ((methoxybenzamidomethyl)norephedrine and related compds. effect on) cardiovascular catechol amine deriv heart catechol amine deriv circulation catechol amine deriv blood pressure catechol amine deriv norephedrine analog heart circulation
Subjects:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Deposited On:19 Nov 2010 09:01
Last Modified:19 Nov 2010 09:01
Item ID:18172
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