Startseite UB

Synthesis of alkoxybenzhydryl akylamines, local anesthetics from Schiff bases and phenyllithium

Thies, Heinrich and Schönenberger, Helmut and Borah, K. (1966) Synthesis of alkoxybenzhydryl akylamines, local anesthetics from Schiff bases and phenyllithium. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft 299 (12), pp. 1031-1038.

Full text not available from this repository.


Abstract

The use of PhLi instead of PhMgBr gave improved yields of the title compds. (I). Thus, a soln. of 0.3 mole 0-, m-, or p-HOC6H4CHO in 150 ml. 2N KOH was treated with 0.103 mole Me2SO4 or Et2SO4 and shaken 5 min. The procedure was repeated twice, then the mixt. was shaken 0.5 hr., treated with 30 ml. 2N KOH and refluxed 0.5 hr. The cooled soln. was extd. with CHCl3, which ext. was dried and evapd. ...

plus


Export bibliographical data

Item Type:Article
Date:1966
Additional information (public):CAN 68:39251 25 Noncondensed Aromatic Compounds 2538-36-5P; 5077-11-2P; 13114-23-3P; 16928-28-2P; 16928-30-6P; 16928-31-7P; 16928-32-8P; 16928-33-9P; 16928-34-0P; 16928-35-1P; 16928-36-2P; 16928-37-3P; 16928-38-4P; 16928-40-8P; 16928-41-9P; 16928-42-0P; 16928-43-1P; 16928-44-2P; 16928-45-3P; 16928-46-4P; 16928-48-6P; 16928-49-7P; 16928-50-0P; 16928-51-1P; 16928-52-2P; 16932-04-0P; 16932-06-2P; 16932-07-3P; 16932-08-4P; 16932-09-5P; 16932-10-8P; 16932-11-9P; 16932-12-0P; 16932-13-1P; 16932-14-2P; 16932-15-3P; 16932-16-4P; 16932-17-5P; 16932-18-6P; 16932-19-7P; 16932-20-0P; 16964-11-7P; 17036-57-6P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 591-51-5 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with Schiff bases)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Identification Number:
ValueType
1968:39251Other
Keywords:Anesthetics (ar-alkoxy-N-alkyl-alpha -phenylbenzylamines as) Schiff bases Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction of, with phenyllithium) AMINES BENZHYDRYL ALKYL BENZHYDRYL ALKYL AMINES ALKYL BENZHYDRYL AMINES
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Petra Gürster
Deposited On:19 Nov 2010 06:28
Last Modified:19 Nov 2010 06:28
Item ID:18205
Owner Only: item control page
  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact