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CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors.

Corbo, Joseph C and Lawrence, Karen A and Karlstetter, Marcus and Myers, Connie A and Abdelaziz, Musa and Dirkes, William and Weigelt, Karin and Seifert, Martin and Benes, Vladimir and Fritsche, Lars G and Weber, Bernhard H F and Langmann, Thomas (2010) CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome research 20 (11), pp. 1512-25.

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Abstract

Approximately 98% of mammalian DNA is noncoding, yet we understand relatively little about the function of this enigmatic portion of the genome. The cis-regulatory elements that control gene expression reside in noncoding regions and can be identified by mapping the binding sites of tissue-specific transcription factors. Cone-rod homeobox (CRX) is a key transcription factor in photoreceptor ...

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Item Type:Article
Date:2010
Institutions:UNSPECIFIED
Identification Number:
ValueType
20693478PubMed ID
10.1101/gr.109405.110DOI
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Thomas Langmann
Deposited On:23 Nov 2010 09:03
Last Modified:23 Nov 2010 09:03
Item ID:18227
Owner Only: item control page
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