Corbo, Joseph C and Lawrence, Karen A and Karlstetter, Marcus and Myers, Connie A and Abdelaziz, Musa and Dirkes, William and Weigelt, Karin and Seifert, Martin and Benes, Vladimir and Fritsche, Lars G and Weber, Bernhard H F and Langmann, Thomas (2010) CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome research 20 (11), pp. 1512-25.
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Approximately 98% of mammalian DNA is noncoding, yet we understand relatively little about the function of this enigmatic portion of the genome. The cis-regulatory elements that control gene expression reside in noncoding regions and can be identified by mapping the binding sites of tissue-specific transcription factors. Cone-rod homeobox (CRX) is a key transcription factor in photoreceptor ...
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|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Yes|
|Deposited On:||23 Nov 2010 09:03|
|Last Modified:||23 Nov 2010 09:03|