Mass, Markus and Simo, Erika and Dragon, Stefanie (2003) Erythroid pyrimidine 5'-nucleotidase: cloning, developmental expression, and regulation by cAMP and in vivo hypoxia. Blood 102 (12), pp. 4198-4205.
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A characteristic process of terminal erythroid differentiation is the degradation of ribosomal RNA into mononucleotides. The pyrimidine mononucleotides can be dephosphorylated by pyrimidine 5'-nucleotidase (P5N-I). In humans, a lack of this enzyme causes hemolytic anemia with ribosomal structures and trinucleotides retained in the red blood cells (RBCs). Although the protein/nucleotide sequence ...
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|Institutions:||Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Rosemarie Baumann|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||09 Dec 2010 06:56|
|Last Modified:||09 Dec 2010 06:56|