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Palladium and copper mediated N-aryl bond formation reactions for the synthesis of biological active compounds

Fischer, Carolin and König, Burkhard (2011) Palladium and copper mediated N-aryl bond formation reactions for the synthesis of biological active compounds. Beilstein Journal of Organic Chemistry (7), pp. 59-74.

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Abstract

N-Arylated aliphatic and aromatic amines are important substituents in many biologically active compounds. In the last few years, transition-metal-mediated N-aryl bond formation has become a standard procedure for the introduction of amines into aromatic systems. While N-arylation of simple aromatic halides by simple amines works with many of the described methods in high yield, the reactions may ...

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Export bibliographical data

Item Type:Article
Date:14 January 2011
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
ValueType
10.3762/bjoc.7.10 DOI
Keywords:biologically active compounds; boronic acid; copper; N-arylation; palladium
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Regina Hoheisel
Deposited On:19 Jan 2011 10:50
Last Modified:19 Jan 2011 10:50
Item ID:19065
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