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Comparison of reduced and standard light application in photodynamic therapy of the eye in two rabbit models

Framme, C. and Flucke, B. and Birngruber, R. (2006) Comparison of reduced and standard light application in photodynamic therapy of the eye in two rabbit models. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 244 (7), pp. 773-281.

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Other URL: http://dx.doi.org/10.1007/s00417-005-0221-2


Abstract

BACKGROUND: Current PDT treatment for age-related macular degeneration uses a standard radiant exposure of 50 J/cm(2) at an irradiance of 600 mW/cm(2). However; there is a general problem with the unusually high irradiance; in fact, the rate of photochemical production of singlet oxygen may be limited by insufficiently oxygenized neovascular tissue. It was the aim of this study to evaluate the ...

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Item Type:Article
Date:July 2006
Institutions:Medicine > Lehrstuhl für Augenheilkunde
Identification Number:
ValueType
16440207PubMed ID
10.1007/s00417-005-0221-2DOI
Keywords:PDT; AMD; Choroidal neovascularization; Radiant exposure; Threshold
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:30 Mar 2007
Last Modified:13 Mar 2014 10:10
Item ID:1931
Owner Only: item control page

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