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A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells

Blindt, Rüdiger and Vogt, Felix and Astafieva, Irina and Fach, Christian and Hristov, Mihail and Krott, Nicole and Seitz, Berthold and Kapurniotu, Aphrodite and Kwok, Connie and Dewor, Manfred and Bosserhoff, Anja-Katrin and Bernhagen, Jürgen and Hanrath, Peter and Hoffmann, Rainer and Weber, Christian (2006) A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells. Journal of the American College of Cardiology 47 (9), pp. 1786-1795.

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Other URL: http://dx.doi.org/10.1016/j.jacc.2005.11.081


Abstract

OBJECTIVES: Novel stents loaded with an integrin-binding cyclic Arg-Gly-Asp peptide (cRGD) were analyzed for their potential to limit coronary neointima formation and to accelerate endothelialization by attracting endothelial progenitor cells (EPCs). BACKGROUND: Re-endothelialization is important for healing after arterial injury. METHODS: Effects of cRGD on EPC number, recruitment in flow, and ...

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Item Type:Article
Date:2 May 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
10.1016/j.jacc.2005.11.081DOI
16682302PubMed ID
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:29 Mar 2007
Last Modified:13 Mar 2014 10:10
Item ID:1940
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