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MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation

Gray, David and Obermann, Ellen C. and Evans, Mark and Hartmann, Arndt and Cooper, Kumarasen and Blaszyk, Hagen (2006) MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation. American journal of clinical pathology 125 (3), pp. 407-412.

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Abstract

We investigated the staining characteristics of serrated polyps with abnormal proliferation (SPAP) using MIB-1 and MCM-2 to determine if they could provide assistance in delineating SPAPs from traditional hyperplastic polyps (HPs). Using published morphologic criteria we reviewed H&E slides of 107 polyps from 80 patients. Thirty-nine (36.4%) polyps met the criteria for SPAP Within a given region, ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
16613344PubMed ID
Keywords:Hyperplastic polyp; Serrated polyp; Serrated neoplasia pathway; MIB-1; MCM-2
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:29 Mar 2007
Last Modified:13 Mar 2014 10:10
Item ID:1943
Owner Only: item control page

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