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Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder

Oers, Johanna M. M. van and Adam, Christoph and Denzinger, Stefan and Stoehr, Robert and Bertz, Simone and Zaak, Dirk and Stief, Christian and Hofstaedter, Ferdinand and Zwarthoff, Ellen C. and van der Kwast, Theodorus H. and Knuechel, Ruth and Hartmann, Arndt (2006) Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder. International journal of cancer. Journal international du cancer 119 (5), pp. 1212-1215.

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Other URL: http://dx.doi.org/10.1002/ijc.21958


Abstract

Flat urothelial hyperplasias (FUHs) in patients with papillary bladder tumours frequently show deletions of chromosome 9, suggesting that FUH could be the first neoplastic step in the development of papillary bladder cancer. FGFR3 mutations are frequent in non-invasive papillary tumours with low risk of progression. Our aim was to investigate the frequency of FGFR3 mutations and deletions of ...

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Item Type:Article
Date:1 September 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
16570285PubMed ID
10.1002/ijc.21958DOI
Keywords:flat urothelial hyperplasia; FGFR3; LOH chromosome 9
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:29 Mar 2007
Last Modified:13 Mar 2014 10:10
Item ID:1945
Owner Only: item control page
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