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Effect of N-acetyl-L-cysteine on ROS production and cell death caused by HEMA in human primary gingival fibroblasts

Spagnuolo, Gianrico and D'Antò, Vincenzo and Cosentino, Claudia and Schmalz, Gottfried and Schweikl, Helmut and Rengo, Sandro (2006) Effect of N-acetyl-L-cysteine on ROS production and cell death caused by HEMA in human primary gingival fibroblasts. Biomaterials 27 (9), pp. 1803-1809.

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Other URL: http://dx.doi.org/10.1016/j.biomaterials.2005.10.022


Abstract

Previous investigations have shown that 2-hydroxyethyl methacrylate (HEMA) causes reactive oxygen species (ROS) production, which in turn affects cell survival and cell death. The purpose of this study was to evaluate the effects of the antioxidant N-acetyl-L-cysteine (NAC) on HEMA-induced toxicity in human primary gingival fibroblasts (HGF). HGF were treated with various concentrations of HEMA ...

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Item Type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie
Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie > Prof. Dr. rer. nat. Helmut Schweikl
Identification Number:
ValueType
16289659PubMed ID
10.1016/j.biomaterials.2005.10.022DOI
Keywords:Dental resin; HEMA; Human gingival fibroblasts; NAC; Reactive oxygen species
Subjects:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Owner: Ute Lange
Deposited On:30 Aug 2007
Last Modified:13 Mar 2014 10:11
Item ID:1950
Owner Only: item control page

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