Naumann, Lydia and Feist, Eugen and Straub, Rainer H. and Burmester, Gerd-Rüdiger and Buttgereit, Frank (2006) Potencies of topical glucocorticoids to mediate genomic and nongenomic effects on human peripheral blood mononuclear cells. Biochemical pharmacology 71 (4), pp. 530-539.
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Other URL: http://dx.doi.org/10.1016/j.bcp.2005.10.045
Several different genomic and nongenomic mechanisms are known to mediate the important anti-inflammatory and immunomodulatory effects of glucocorticoids (GC). Genomic effects are the most important while the clinical relevance of nongenomic actions is still a matter of debate. We therefore investigated whether beclometasone and clobetasol are particularly suitable for topical application because ...
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|Date:||14 February 2006|
|Institutions:||Medicine > Lehrstuhl für Innere Medizin I|
|Keywords:||Human peripheral blood mononuclear cells; Systemic and topical glucocorticoids; Energy metabolism; Apoptosis; IL-6; Genomic and nongenomic glucocorticoid effects|
|Subjects:||500 Science > 570 Life sciences|
600 Technology > 610 Medical sciences Medicine
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||30 Aug 2007|
|Last Modified:||13 Mar 2014 10:11|