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Potencies of topical glucocorticoids to mediate genomic and nongenomic effects on human peripheral blood mononuclear cells

Naumann, Lydia and Feist, Eugen and Straub, Rainer H. and Burmester, Gerd-Rüdiger and Buttgereit, Frank (2006) Potencies of topical glucocorticoids to mediate genomic and nongenomic effects on human peripheral blood mononuclear cells. Biochemical pharmacology 71 (4), pp. 530-539.

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Other URL: http://dx.doi.org/10.1016/j.bcp.2005.10.045


Abstract

Several different genomic and nongenomic mechanisms are known to mediate the important anti-inflammatory and immunomodulatory effects of glucocorticoids (GC). Genomic effects are the most important while the clinical relevance of nongenomic actions is still a matter of debate. We therefore investigated whether beclometasone and clobetasol are particularly suitable for topical application because ...

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Item Type:Article
Date:14 February 2006
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
16343445PubMed ID
10.1016/j.bcp.2005.10.045DOI
Keywords:Human peripheral blood mononuclear cells; Systemic and topical glucocorticoids; Energy metabolism; Apoptosis; IL-6; Genomic and nongenomic glucocorticoid effects
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Deposited On:30 Aug 2007
Last Modified:13 Mar 2014 10:11
Item ID:1952
Owner Only: item control page

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