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Photodegradation of some quinolones used as antimicrobial therapeutics

Tiefenbacher, E. M. and Haen, Ekkehard and Przybilla, B. and Kurz, H. (1994) Photodegradation of some quinolones used as antimicrobial therapeutics. Journal of pharmaceutical sciences 83 (4), pp. 463-467.

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Abstract

The photostability of the fluoroquinolones ciprofloxacin (CPX), ofloxacin (OFX), and fleroxacin (FLX) toward ultraviolet irradiation (UVA) and room light was investigated in dilute aqueous solutions. A series of photoproducts was observed by high-performance liquid chromatography (HPLC) for all three drugs. As little as 1 h of exposure to room light was enough for the formation of detectable ...

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Item Type:Article
Date:1994
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
8046597PubMed ID
Classification:
NotationType
Anti-Infective Agents/radiation effectsMESH
Chromatography, High Pressure LiquidMESH
Ciprofloxacin/radiation effectsMESH
Fleroxacin/radiation effectsMESH
LightMESH
Mass SpectrometryMESH
Ofloxacin/radiation effectsMESH
PhotochemistryMESH
Spectrophotometry, UltravioletMESH
Ultraviolet RaysMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:17 Feb 2011 07:39
Last Modified:13 Mar 2014 16:53
Item ID:19632
Owner Only: item control page

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