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Über die Bedeutung der Applikationsgeschwindigkeit für die pharmakokinetischen Parameter von Azlocillin und Mezlocillin (=The effect of infusion rate on pharmacokinetic parameters of azlocillin and mezlocillin)

Haen, Ekkehard and Remien, J. and Richter, E. and Frank, U. and Adam, D. (1985) Über die Bedeutung der Applikationsgeschwindigkeit für die pharmakokinetischen Parameter von Azlocillin und Mezlocillin (=The effect of infusion rate on pharmacokinetic parameters of azlocillin and mezlocillin). Arzneimittel-Forschung = Drug research 35 (5), pp. 864-868.

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Abstract

Azlocillin (Securopen) and mezlocillin (Baypen) were given to 3 healthy subjects as intravenous infusion. The dose of 4 g was administered to each person within 5, 15, and 30 min in a randomized crossover design. Using HPLC the unchanged penicillin antibiotics were determined quantitatively, their metabolites were assessed qualitatively. The same specimens were also studied by means of a bioassay ...

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Item Type:Article
Date:1985
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
4026911PubMed ID
Classification:
NotationType
AdultMESH
Azlocillin/urineMESH
Chromatography, High Pressure LiquidMESH
Half-LifeMESH
HumansMESH
Infusions, ParenteralMESH
KineticsMESH
MaleMESH
Mezlocillin/urineMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:17 Mar 2011 08:02
Last Modified:13 Mar 2014 17:05
Item ID:19648
Owner Only: item control page
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