Haen, Ekkehard and Remien, J. and Richter, E. and Frank, U. and Adam, D. (1985) Über die Bedeutung der Applikationsgeschwindigkeit für die pharmakokinetischen Parameter von Azlocillin und Mezlocillin (=The effect of infusion rate on pharmacokinetic parameters of azlocillin and mezlocillin). Arzneimittel-Forschung = Drug research 35 (5), pp. 864-868.
Azlocillin (Securopen) and mezlocillin (Baypen) were given to 3 healthy subjects as intravenous infusion. The dose of 4 g was administered to each person within 5, 15, and 30 min in a randomized crossover design. Using HPLC the unchanged penicillin antibiotics were determined quantitatively, their metabolites were assessed qualitatively. The same specimens were also studied by means of a bioassay ...
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|Institutions:||Medicine > Lehrstuhl für Psychiatrie und Psychotherapie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||17 Mar 2011 08:02|
|Last Modified:||13 Mar 2014 17:05|