Roesch, Alexander and Becker, Bernd and Schneider-Brachert, Wulf and Hagen, Ilja and Landthaler, Michael and Vogt, Thomas (2006) Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells. The Journal of investigative dermatology 126 (8), pp. 1850-1859.
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Other URL: http://dx.doi.org/10.1038/sj.jid.5700324
The loss of cell cycle control in malignant melanomas is thought to be due to a lack of retinoblastoma protein (pRb) activity. We have recently reported a progressive deficiency of the retinoblastoma-binding protein 2-homolog 1 (RBP2-H1) in advanced and metastatic melanomas in vivo, suggesting a role of RBP2-H1 in loss of pRb-mediated control. Therefore, in this study, we re-established the ...
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|Institutions:||Medicine > Lehrstuhl für Dermatologie und Venerologie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||30 Mar 2007|
|Last Modified:||13 Mar 2014 10:11|