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Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1

Bucher, Michael and Kees, Frieder K. and Messmann, Barbara and Lunz, Dirk and Rath, Stephan and Zelenka, Marek and Schlitt, Hans J. and Hobbhahn, Jonny (2006) Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. European journal of pharmacology 536 (3), pp. 296-300.

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Other URL: http://dx.doi.org/10.1016/j.ejphar.2006.03.009


Abstract

Our study aimed to determine the role of cyclooxygenase-2 in the release of prostaglandin-(PG)-I2 following mesenteric traction during abdominal surgery. In a prospective double-blind, randomized, placebo-controlled study, 40 patients electively scheduled for non-laparoscopic abdominal surgery, were pretreated with the cyclooxygenase-2 inhibitor parecoxib (n=20) or placebo (n=20). Heart rate, ...

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Item Type:Article
Date:1 May 2006
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
10.1016/j.ejphar.2006.03.009DOI
16581062PubMed ID
Keywords:Mesenteric traction; Cyclooxygenase-inhibitor; Prostaglandin; Hemodynamics; Oxygenation
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Ute Lange
Deposited On:30 Aug 2007
Last Modified:13 Mar 2014 10:11
Item ID:1973
Owner Only: item control page

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