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Influence of the cholinergic agonist RS 86 on normal sleep: sex and age effects

Riemann, D. and Joy, D. and Höchli, D. and Lauer, C. and Zulley, Jürgen and Berger, M. (1988) Influence of the cholinergic agonist RS 86 on normal sleep: sex and age effects. Psychiatry research 24 (2), pp. 137-147.

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Abstract

In 36 healthy control subjects (21 females, 15 males; age range 18-65 years; mean age 41.8 years, SD 15.6 years), a bedtime dose of 1.5 mg RS 86, an orally acting cholinergic agonist, shortened rapid eye movement (REM) latency, increased REM sleep, and decreased slow-wave sleep. Six of the subjects (greater than 40 years old) even displayed sleep-onset REM periods after the drug. Results of the ...

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Item Type:Article
Date:1988
Institutions:Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Identification Number:
ValueType
3406234PubMed ID
10.1016/0165-1781(88)90056-XDOI
Classification:
NotationType
AdolescentMESH
AdultMESH
Affect/drug effectsMESH
AgedMESH
Aging/physiologyMESH
FemaleMESH
HumansMESH
MaleMESH
Middle AgedMESH
Parasympathomimetics/pharmacologyMESH
Reaction Time/physiologyMESH
Sex FactorsMESH
Sleep/physiologyMESH
Sleep, REM/physiologyMESH
Succinimides/pharmacologyMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:01 Mar 2011 07:11
Last Modified:13 Mar 2014 16:58
Item ID:19872
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