Wiegand, M. and Berger, M. and Zulley, Jürgen and von Zerssen, D. (1986) The Effect of Trimipramine on Sleep in Patients with Major Depressive Disorder. Pharmacopsychiatry 19 (4), pp. 198-199.
Antidepressants generally inhibit REM sleep. This effect is often considered to be a crucial feature of these drugs. Trimipramine, however, is a tricyclic antidepressant which does not inhibit REM sleep in rats (Khazan and Brown, 1970; Wassennan and Khazan, 1971). This result could be confirmed in man: Dunleavy et al. (1972) administered this drug to two healthy volunteers and found no ...
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|Institutions:||Medicine > Lehrstuhl für Psychiatrie und Psychotherapie|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||04 Mar 2011 13:24|
|Last Modified:||13 Mar 2014 17:01|