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Multiplex bacterial growth monitoring in 24-well microplates using a dual optical sensor for dissolved oxygen and pH

Kocincová, Anna S. and Nagl, Stefan and Arain, Sarina and Krause, Christian and Borisov, Sergey M. and Arnold, Matthias and Wolfbeis, Otto S. (2008) Multiplex bacterial growth monitoring in 24-well microplates using a dual optical sensor for dissolved oxygen and pH. Biotechnology and Bioengineering 100 (3), pp. 430-438.

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Abstract

Non-invasive, simultaneous optical monitoring of oxygen and pH during bacterial cultivation in 24-well microplates is presented using an integrated dual sensor for dissolved oxygen and pH values. The dual sensor is based on oxygen-sensitive organosilica microparticles and pH-sensitive microbeads from a polymethacrylate derivative embedded into a polyurethane hydrogel. The readout is based on a ...

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Item Type:Article
Date:15 June 2008
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Otto S. Wolfbeis)
Identification Number:
ValueType
DOI: 10.1002/bit.21793DOI
Keywords:oxygen sensing; pH sensing; microbioreactor; bioprocess; dual sensor; fluorescence
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Martin Kaiser
Deposited On:18 Mar 2011 07:30
Last Modified:13 Mar 2014 17:02
Item ID:20056
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