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Chameleon Labels for Staining and Quantifying Proteins

Wetzl, Bianca K. and Yarmoluk, Sergiy M. and Craig, Douglas B. and Wolfbeis, Otto S. (2004) Chameleon Labels for Staining and Quantifying Proteins. Angewandte Chemie International Edition 43 (40), pp. 5400-5402.

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Abstract

Glowing marks: A new class of protein stains, the pyrylium dyes, undergo a strong color change (typically from blue to red, see picture) on covalently binding to proteins. While the free stains are almost nonfluorescent, the protein-conjugated forms are highly fluorescent. The dyes do not alter the charge of a protein, and thus do not change its electrophoretic properties. The stains also can be ...

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Item Type:Article
Date:11 October 2004
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Otto S. Wolfbeis)
Identification Number:
ValueType
10.1002/anie.200460508DOI
Keywords:electrophoresis;fluorescent probes;protein assay;proteomics
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Petra Gürster
Deposited On:06 Apr 2011 09:16
Last Modified:13 Mar 2014 17:10
Item ID:20383
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