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Inhibition of infectious human immunodeficiency virus type 1 particle formation by Gag protein-derived peptides

Niedrig, M. and Gelderblom, H. R. and Pauli, G. and März, J. and Bickhard, H. and Wolf, Hans J. and Modrow, Susanne (1994) Inhibition of infectious human immunodeficiency virus type 1 particle formation by Gag protein-derived peptides. The Journal of general virology 75 ( P, pp. 1469-1474.

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Abstract

Sequential overlapping Gag protein-derived oligopeptides of human immunodeficiency virus type 1 (HIV-1) 22 to 24 amino acids long, were synthesized and tested in vitro for antiviral activity. Two synthetic peptides, one derived from the matrix protein p17 (NPGLLETSEGCRQ, amino acids 47 to 59) and one located in the capsid protein p24 (PAATLEEMMTA, amino acids 339 to 349) inhibited the production ...

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Item Type:Article
Date:1994
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
8207412PubMed ID
Classification:
NotationType
Amino Acid SequenceMESH
Gene Products, gag/pharmacologyMESH
HIV-1/pathogenicityMESH
HumansMESH
Molecular Sequence DataMESH
MorphogenesisMESH
Oligopeptides/pharmacologyMESH
Sequence AlignmentMESH
Sequence Homology, Amino AcidMESH
Structure-Activity RelationshipMESH
T-Lymphocytes/microbiologyMESH
Tumor Cells, CulturedMESH
Virus Replication/drug effectsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:06 Apr 2011 07:55
Last Modified:13 Mar 2014 17:10
Item ID:20393
Owner Only: item control page
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