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Expression of proteins encoded by Epstein-Barr virus trans-activator genes depends on the differentiation of epithelial cells in oral hairy leukoplakia

Becker, J. and Leser, U. and Marschall, M. and Langford, A. and Jilg, Wolfgang and Gelderblom, H. and Reichart, P. and Wolf, Hans J. (1991) Expression of proteins encoded by Epstein-Barr virus trans-activator genes depends on the differentiation of epithelial cells in oral hairy leukoplakia. Proceedings of the National Academy of Sciences of the United States of America : PNAS 88 (19), pp. 8332-8336.

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Abstract

The Epstein-Barr virus (EBV) immediate early gene product BZLF1 was localized by indirect immunofluorescence to the cytoplasm of the basal epithelial layer at the lateral border and dorsum of tongue in human immunodeficiency virus-infected and -seronegative patients. Two biopsies of oral hairy leukoplakia revealed a sporadic cytoplasmic staining of the BHRF1 and BRLF1 gene products in the basal ...

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Item Type:Article
Date:1991
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
1656439PubMed ID
Classification:
NotationType
Cell DifferentiationMESH
DNA-Binding Proteins/metabolismMESH
Epithelium/pathologyMESH
Fluorescent Antibody TechniqueMESH
Gene Expression Regulation, ViralMESH
Genes, ViralMESH
HIV Seropositivity/microbiologyMESH
Herpesvirus 4, Human/geneticsMESH
HumansMESH
Leukoplakia, Oral/pathologyMESH
Mouth Mucosa/pathologyMESH
Tongue/pathologyMESH
Trans-ActivatorsMESH
Viral Proteins/metabolismMESH
Viral Structural Proteins/geneticsMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:12 Apr 2011 08:00
Last Modified:13 Mar 2014 17:14
Item ID:20465
Owner Only: item control page

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