Reichart, P. A. and Langford, A. and Gelderblom, H. R. and Pohle, H. D. and Becker, J. and Wolf, Hans J.
Oral hairy leukoplakia: observations in 95 cases and review of the literature.
Journal of oral pathology & medicine 18 (7), pp. 410-415.
Oral hairy leukoplakia (HL) was observed in 25.4% of 373 HIV-seropositive patients (n = 95). 87 were men of an average age of 37.1 yr, 8 were women (30.3 yr). 71.6% of the patients were male homosexuals. At initial diagnosis of HL the majority of cases was classified as CDC IVc1 (45.3%) and CDC II (22.1%). Average CD4/CD8 ratio (n = 19) was 0.24 with a range of 0.04-1.0. Thirty biopsies of HL revealed some of the histologic features thought to be characteristic. In only 20 of 30 biopsies EB-virus-specific-capsid antigen was detected. The problems of clinical and histological diagnosis of HL are discussed. Further strict criteria are necessary in order to define HL more distinctly.
|Institutions:|| Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene|
|Aged, 80 and over||MESH|
|Herpesvirus 4, Human||MESH|
|Tumor Virus Infections/pathology||MESH|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||15 Apr 2011 09:14|
|Last Modified:||21 Jul 2011 02:11|