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Truncated versions of the two major Epstein-Barr viral glycoproteins (gp250/350) are secreted by recombinant Chinese hamster ovary cells

Motz, M. and Deby, G. and Wolf, Hans J. (1987) Truncated versions of the two major Epstein-Barr viral glycoproteins (gp250/350) are secreted by recombinant Chinese hamster ovary cells. Gene 58 (1), pp. 149-154.

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Abstract

The expression of the two Epstein-Barr virus (EBV) major membrane proteins gp250/350 (MA-BLLF1) on the surface of recombinant CHO clones cannot be amplified by methotrexate (MTX) selection, perhaps due to toxic effects of these membrane proteins. After removal of sequences encoding the part of the glycoproteins responsible for membrane anchorage, the gp250/350 is secreted into the medium. ...

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Item Type:Article
Date:1987
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Identification Number:
ValueType
2826297PubMed ID
Classification:
NotationType
AnimalsMESH
Antigens, Viral/isolation & purificationMESH
Clone Cells/secretionMESH
Cloning, MolecularMESH
CricetinaeMESH
CricetulusMESH
FemaleMESH
Gene AmplificationMESH
Herpesvirus 4, Human/immunologyMESH
OvaryMESH
PlasmidsMESH
Viral Matrix Proteins/secretionMESH
Viral Vaccines/isolation & purificationMESH
Subjects:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Owner: Universitätsbibliothek Regensburg
Deposited On:15 Apr 2011 08:40
Last Modified:13 Mar 2014 17:16
Item ID:20540
Owner Only: item control page
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