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Synthetic efforts towards the total synthesis of furanolactone cembranoids and discovery of antimicrobial and anticancer benzyloxylated congeners

URN to cite this document: urn:nbn:de:bvb:355-epub-207048

Macabeo, Allan Patrick (2012) Synthetic efforts towards the total synthesis of furanolactone cembranoids and discovery of antimicrobial and anticancer benzyloxylated congeners. PhD, Universität Regensburg

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Abstract (English)

Within the framework of the study’s interest on bioactive structure synthesis and discovery, chemical explorations have been undertaken to develop methods to synthesize complex, highly oxidized furanolactone cembranoids and antiproliferative benzyloxylated derivatives. Bulk of the study has been centered on synthetic strategies en route to the furanocembranoids bielschowskysin, verrillin and ...

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Translation of the abstract (German)

Hauptinteresse dieser Arbeit war die Synthese und Entdeckung von bioaktiven Strukturen. Chemische Untersuchungen wurden durchgeführt um Methoden zu entwickeln, um komplexe, hoch oxygenierte, Furanolakton Cembranoide und um antiproliverative Benzyloxygenierte Derivate davon herzustellen. Der Großteil dieser Arbeit war auf Synthesestrategien in Richtung der Furancembranoiden Bielschowskysin, ...

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Item Type:Thesis of the University of Regensburg (PhD)
Date:8 May 2012
Referee:Prof. Dr. Oliver Reiser and Prof. Dr. Burkhard König and Prof. Dr. Jörg Heilmann
Date of exam:20 April 2011
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser
Keywords:total synthesis, cyclopropane carbaldehyde, furanolactone cembranoids, benzyloxylated, antimicrobial, anticancer
Subjects:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:08 May 2012 09:07
Last Modified:13 Mar 2014 18:48
Item ID:20704
Owner Only: item control page

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