Hümmer, H. P. and Segerer, Hugo
Verhütung von Komplikationen bei congenitalen Zwerchfelldefekten = Prevention of complications in congenital diaphragmatic defects.
Der Chirurg 57 (3), pp. 159-164.
The mortality rate from congenital diaphragmatic hernia is not much better than it was 25 years ago. Most children, who are more than 24 hours of age at operation, survive. On the first day of life postoperative mortality is about 47%. Pediatric surgical problems are stabilization of the diaphragm and abdominal decompression. Some risk patients may be brought out of the fatal zone by high frequency ventilatory support and pharmacologic reversal of the fetal circulation. The most important causes of death are pulmonary hypoplasia with abnormal pulmonary vascular reactivity and persistent fetal circulation, iatrogenic pneumothorax, interstitial emphysema, mediastinal shifting with subsequent pulmonary hypertension and right to left shunting, and associated cardiac malformations.
|Institutions:|| Medicine > Lehrstuhl für Kinder- und Jugendmedizin|
|Intraoperative Complications/prevention & control||MESH|
|Postoperative Complications/prevention & control||MESH|
|Subjects:||600 Technology > 610 Medical sciences Medicine|
|Refereed:||Yes, this version has been refereed|
|Created at the University of Regensburg:||Unknown|
|Deposited On:||23 May 2011 08:44|
|Last Modified:||21 Jul 2011 02:13|